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	Determining the optimal patch size for sparse image representation Šuránek, David ; Zátyik, Ján (referee) ; Špiřík, Jan (advisor) Introduction of this thesis is dedicated to the description of basic concepts and algorithms for image processing using sparse representation. Furthermore there is mentioned neural network model called Restricted Boltzmann machine, which is in the practical part of the thesis subject of behaving observation in the task of determining the optimal block size for extrapolation using K-SVD algorithm Detailed record
	Enhancement of the efficacy of DNA vaccines against the cervical cancer with helper epitopes Peřinová, Lucie ; Brábek, Jan (referee) ; Šmahel, Michal (advisor) The human papillomaviruses (HPV) are the etiological agent of cervical cancer. Their oncoproteins E6 and E7 are involved in the transformation of an infected cell into a neoplastic cell, thereby they are the target antigenes for the development of DNA vaccines. Helper epitopes activating CD4+ T cells are under study because they enhance the efficacy of DNA vaccines through increasing the number of cytotoxic T lymphocytes and thereby removal of the tumor. There are already being used epitopes derived directly from oncoproteins, synthetic epitopes or bacterial epitopes for the general enhancement of the immune response. Sufficient number of comparative studies which would establish the exactly most efficient helper epitopes has not been made. The research aims at combining more peptide types using immunostimulatory molecules. Detailed record
	Determining the optimal patch size for sparse image representation Šuránek, David ; Zátyik, Ján (referee) ; Špiřík, Jan (advisor) Introduction of this thesis is dedicated to the description of basic concepts and algorithms for image processing using sparse representation. Furthermore there is mentioned neural network model called Restricted Boltzmann machine, which is in the practical part of the thesis subject of behaving observation in the task of determining the optimal block size for extrapolation using K-SVD algorithm Detailed record

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